Mechano Growth Factor 2550 Mechano growth factor (MGF) is a structural modification of insulin-like growth factor (IGF-1), a variation in the form of IGF-IEs. Mechano growth factorproduction is observed as a result of physical exertion or muscle tissue trauma, because MGF is a reducing substance for muscles. IGF-1 has a number of unique isomers (proteins having similarities in the structural