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Dihydrotestosterone is an androgen hormone responsible for the development of male characteristics such as the voice and body hair. Therefore, the increase in Dihydrotestosterone (DHT) that comes hand in hand with the use of some steroids can sometimes cause hair loss. In order to reduce the risk of this side effect, steroid users take hair loss pills along with their steroid cycle.
Types of hair loss pills
There are two main types of pills that are most effective at treating hair loss. These are drugs that contain Dutasteride, or drugs that contain Finasteride. These substances are both reductase inhibitors, which reduce this side effect by reducing the level of androgenic activity in the skin and scalp. Reductase inhibitors are only applicable with Testosterone, Methyltestosterone, and Fluoxymesterone. These three drugs are converted into potent dihydrotestosterone derivatives of the reductase enzyme.
How do reductase inhibitors work?
Finasteride is an inhibitor of 5α-reductase, in particular type II and III isozymes. When 5-reductase is inhibited, Finasteride prevents the conversion of testosterone into dihydrotestosterone (DHT), type II and III isozymes lead to a decrease in serum DHT levels by about 65-70%, and in the prostate, the level of DHT is up to 85-90%, where there is a Type II isozyme. Unlike triple inhibitors of all three 5a-reductase isozymes, such as Dutasteride, which can reduce total body DHT levels by more than 99%, Finasteride does not completely suppress DHT production as it lacks a significant inhibitory effect on the isozyme 5α-reductase I, 100 times less affinity in I compared to II.
Simply put, studies show that 0.1mg of Dutasteride reduces Dihydrotestosterone levels in the same way as 5.0mg of Finasteride, which is approximately -70%.
In terms of how they affect hair density, then 0.1mg of Dutasteride is similar in effectiveness to 5mg of Finasteride and on average gives you +72 hairs per 2.54 cm (1 inch) around the scalp.
Where can I buy hair loss pills?
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