Lyothoronine is a hormone similar to thyroxine, produced by the thyroid gland; It is used for the treatment of diseases accompanied by an insufficient function of the thyroid gland. It is prescribed inside or in injections; Has a quick but short-term effect on the body. Freeze drying is a method of fixing histological specimens, leading to minimal chemical and physical changes in them.
Characteristics of the substance Lyotyronin
Synthetic thyroid hormone, levorotatory isomer of triiodothyronine.
Pharmacological action – replenishing deficiency of hormones of the thyroid gland.
Increases the need for tissues in oxygen, stimulates Liothyronine (T3) growth and differentiation of tissues, increases the level of basal metabolism (proteins, fats and carbohydrates). In small doses anabolic, and in large – catabolic effect. Inhibits the production of thyroid-stimulating hormone. After oral administration, 95% is absorbed within 4 hours. The latent period is 4-8 hours. It binds to proteins in the blood. The maximum pharmacological effect occurs in 2-3 days. T1 / 2 – 2,5 days.
Application of the substance Lyotyronin
Hypothyroidism (primary, secondary), myxedema, cretinism, cerebrohypophyseal diseases with hypothyroid conditions, hypothyroid obesity, endemic Lioprime 25mcg and sporadic goiter (relapse prevention), thyroid cancer (suppressive therapy), hypothyroidism diagnostics.
Hypersensitivity, untreated thyrotoxicosis, ischemic heart disease, myocarditis, untreated adrenal insufficiency, cachexia.
Restrictions on the use
Tachycardia, tachyarrhythmia, heart failure, diabetes, elderly.
Individual. For adults at the beginning of treatment Lioprime 25mcg, the dose is 10-20 mcg / day, maintaining a dose of 20-100 mcg / day. The daily dose should be divided into 3 divided doses.
On the part of the endocrine system: possibly worsening of the course of diabetes mellitus; Increased manifestations of insufficiency of adrenal cortex function; Symptoms of hyperthyroidism – palpitation, increased sweating.