Isotretinoin – A-vitamin-like agent, which has anti-inflammatory, anti-acne, dermatoprotective and anti-seborrheic effect.
Form of issue and composition
Isotretinoin is available in the form Tretizen 20 of capsules and tablets containing 10 or 20 mg of the same active ingredient.
Dosing and Administration
Tablets / capsules Isotretinoin Tretizen 20 should be taken orally, preferably during meals. Specific dosage of the doctor in each case picks up individually, tk. The therapeutic effectiveness of the drug and its side effects are dose-dependent and may have varying degrees of severity in different patients. As a rule, treatment begins with 0.1 mg / kg / day. After a month, depending on the tolerability and effectiveness of Isotretinoin, the dose is increased by 0.1-1 mg / kg / day. The average daily dosage is 0.4-0.5 mg per each kilogram of the patient’s body weight in 2 divided doses. In severe disease and with acne lesions, it is increased to 2 mg / kg / day. Duration of Isotretinoin (Accutane) application is from 16 to 24 weeks. If necessary, repeat courses of treatment at intervals of not less than 8 weeks. Patients with severe renal insufficiency drug prescribed at a dose of 10 mg per day. Depending on the response to ongoing therapy and the severity of side effects, dosage can be adjusted. If the amount of rashes decreased by at least 70% during 16-24 weeks of taking Isotretinoin, the treatment is stopped. When confirming the recurrent or persistent course of the disease, the second course of therapy is carried out with a break of at least 2 months.
Tretiva – 20 (Isotretinoin) Capsules | Treatment For Acne Pimples | Review Hindi
Isotretinoin is the active ingredient of the following medicinal products: 13-cis-Retinoic acid, Accutane, Acnecutane, Retasol, Retinoic ointment, Roaccutane, Soret.