Masteron 100 10 ampoules (drastanolone propionate) is perhaps one of the most “exotic” androgenic anabolic steroids (AAS) used by athletes. Originally developed as an antiestrogen (called Masteril), the drug was used to treat breast cancer. It has been widely used in the treatment of breast cancer in combination with SMER (selective estrogen receptor modulator) Tamoxifen (or Nolvadex) and has significantly reduced the level of estrogen in women who underwent such treatment. Today, for various reasons, it is rarely used for these purposes, however for many athletes, and professional bodybuilders in particular, the masteron 100 remains an almost unsung favorite among anabolic steroid preparations.
The fact that the masteron was used as an antiestrogen allows us to assume about some of its properties. Masteron is a derivative of DHT (dihydrotestosterone) and is not converted to estrogen by aromatization. It is believed that the anti-estrogenic properties of the masteron 100 may be partly related either to inhibition of the synthesis of the aromatase enzyme or to direct effects on estrogens, Drostanolone propionate (Masteron) blocking its binding to estrogen receptors. In any case, this makes the masterone a useful tool for those who use steroid compounds that are converted to estrogen (which many do, given that the main basis for most cycles is testosterone). Inhibiting the aromatase enzyme, the masteron interferes with the transformation of free testosterone into estrogen by aromatization. This serves not only to a slight increase in the amount of active free testosterone in the circulatory system (making testosterone more effective than in the system without the participation of the master), but also negates the side effects that are a consequence of the high level of estrogen. These side effects include gynecomastia and fluid retention / swelling. Conversely, if the masteron actually blocks the binding of estrogens to estrogen receptors, even if the aromatization of testosterone occurs, its action will be limited by the inability of estrogen to bind to estrogen receptors. Thus, using this mechanism, when using the masteron, the effect of excessive estrogen production through aromatization will also be limited.
Masteron 100 has not only antiestrogenic properties, but (being a derivative of DHT) has anabolic and androgenic qualities. Although theoretically, the masteron is not considered a very strong androgen, in fact it has a stronger androgenic effect than can be expected. The use of a masteron, which is an androgenic anabolic steroid, reduces the natural production of testosterone. Therefore, one should not think that the master can be used as an alternative in post-course therapy. Despite the anti-estrogenic effect, it will inhibit recovery.
Due to the influence of the masteron on the side effects of estrogenic origin, it is very useful for drying (especially in professional bodybuilding). An increase in the level of estrogens leads to a fluid retention, and the master interferes with this. And many say that the masteron gives the muscles not only a feeling of fullness and hardness, but also an amazingly “pumped up” look. Using masteron (in combination with other appropriate drugs) with a low level of subcutaneous fat allows you to achieve an accentuated relief of even the smallest details of the muscles, highlighting all the muscle fibers. Masteron helps to get rid of excess fluid between muscles and skin, giving the body a very relief appearance (with a minimal fat layer). Few of the steroid drugs have such an effect on the muscles, like the masteron.
Many say that it makes no sense to use the masteron if the fat content in the body exceeds 10-12%. Such judgments have a basis: it is necessary to understand that at a higher fat level the muscular relief will not look like the one described above. However, with such antiestrogenic properties, I do not consider it unnecessary. These properties make it possible not to use other auxiliary preparations during the course, which may have other undesirable side effects. In addition, the master can work in conjunction with other steroids, enhancing their effect. Masteron, however, is not recommended for beginners, since at this stage there is no need for it.